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Rina Aharoni Selected Research

Glatiramer Acetate (Copaxone)

12/2021Neuroprotective Effect of Glatiramer Acetate on Neurofilament Light Chain Leakage and Glutamate Excess in an Animal Model of Multiple Sclerosis.
1/2020Glatiramer acetate increases T- and B -regulatory cells and decreases granulocyte-macrophage colony-stimulating factor (GM-CSF) in an animal model of multiple sclerosis.
11/2019Cognitive impairment in an animal model of multiple sclerosis and its amelioration by glatiramer acetate.
3/2019Glatiramer Acetate: from Bench to Bed and Back.
4/2014Oligodendrogenesis and myelinogenesis during postnatal development effect of glatiramer acetate.
3/2013The mechanism of action of glatiramer acetate in multiple sclerosis and beyond.
2/2013Magnetic resonance imaging characterization of different experimental autoimmune encephalomyelitis models and the therapeutic effect of glatiramer acetate.
5/2011Beneficial effect of glatiramer acetate treatment on syndecan-1 expression in dextran sodium sulfate colitis.
8/2010Glatiramer acetate reduces Th-17 inflammation and induces regulatory T-cells in the CNS of mice with relapsing-remitting or chronic EAE.
11/2009Neuroprotection and neurogeneration in MS and its animal model EAE effected by glatiramer acetate.
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Rina Aharoni Research Topics

Disease

22Multiple Sclerosis
01/2022 - 05/2002
18Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
12/2021 - 05/2002
6Colitis
05/2011 - 10/2004
5Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
05/2011 - 02/2005
4Inflammation (Inflammations)
12/2019 - 11/2008
4Demyelinating Diseases (Demyelinating Disease)
12/2019 - 08/2008
3Pathologic Processes
03/2019 - 11/2003
3Disease Progression
11/2014 - 08/2010
2Relapsing-Remitting Multiple Sclerosis
03/2019 - 12/2004
2Neoplasms (Cancer)
01/2014 - 09/2010
1Cognitive Dysfunction
11/2019
1Metabolic Syndrome (Dysmetabolic Syndrome X)
10/2015
1Encephalomyelitis (Myeloencephalitis)
10/2014
1Infections
01/2014
1Gliosis
10/2012
1Chronic Disease (Chronic Diseases)
10/2012
1Central Nervous System Infections (Central Nervous System Infection)
09/2010
1Neurodegenerative Diseases (Neurodegenerative Disease)
07/2009
1Nervous System Diseases (Neurological Disorders)
12/2007
1Body Weight (Weight, Body)
02/2005
1Crohn Disease (Crohn's Disease)
02/2005
1Weight Loss (Weight Reduction)
10/2004

Drug/Important Bio-Agent (IBA)

23Glatiramer Acetate (Copaxone)FDA Link
12/2021 - 05/2002
13Pharmaceutical PreparationsIBA
03/2019 - 11/2003
7CytokinesIBA
03/2019 - 09/2003
6Therapeutic UsesIBA
01/2020 - 02/2005
5Immunologic Factors (Immunomodulators)IBA
05/2011 - 01/2005
4Peptides (Polypeptides)IBA
01/2022 - 01/2016
3Myelin-Oligodendrocyte GlycoproteinIBA
12/2021 - 01/2016
3AntibodiesIBA
01/2017 - 01/2016
3Sulfonic AcidsIBA
10/2007 - 10/2004
2tuftsin-phosphorylcholineIBA
02/2020 - 12/2019
2Brain-Derived Neurotrophic Factor (BDNF)IBA
10/2012 - 12/2005
2Dextrans (Dextran)FDA Link
05/2011 - 11/2008
2Transforming Growth Factor beta (TGF-beta)IBA
11/2008 - 10/2007
2Dextran SulfateIBA
10/2007 - 07/2006
2Nerve Growth Factors (Neurotrophins)IBA
12/2005 - 11/2003
1Myelin Basic ProteinIBA
01/2022
1Immunoglobulin M (IgM)IBA
01/2022
1Glutamic Acid (Glutamate)FDA Link
12/2021
1Neuroprotective AgentsIBA
12/2021
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
01/2020
1Choline (Choline Chloride)IBA
12/2016
1LipidsIBA
01/2016
1AntigensIBA
01/2016
1EpitopesIBA
01/2016
1PerforinIBA
10/2015
1Interferon Type IIBA
10/2014
1Biomarkers (Surrogate Marker)IBA
10/2014
1Proteins (Proteins, Gene)FDA Link
02/2013
1Glycoproteins (Glycoprotein)IBA
02/2013
1laquinimodIBA
10/2012
1sodium sulfate (sodium bisulfate)FDA LinkGeneric
05/2011
1Syndecan-1 (Syndecan 1)IBA
05/2011
1Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA
05/2011
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2008
1Transcription Factors (Transcription Factor)IBA
11/2008
1Messenger RNA (mRNA)IBA
11/2008
1Nitric Oxide (Nitrogen Monoxide)FDA Link
09/2003

Therapy/Procedure

5Therapeutics
03/2019 - 07/2009
4Immunomodulation
04/2014 - 11/2008
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
10/2015
1Transplantation
01/2014
1Injections
12/2005
1Rectal Administration
02/2005
1Oral Administration
12/2004
1Mucosal Administration
05/2002